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Dose titration

The image shows an orange prescription pill bottle tipped on its side, with small white round tablets spilling out onto a light blue surface.

Dose titration is the process of gradually changing (titrating) the dose of a drug to get the best effect while minimizing side effects.

In ME/CFS, titrating up to a target dose is particularly important. Many people with ME/CFS have chemical and other sensitivities, which means their body reacts harshly to new things introduced to their system. Starting at lower doses and working up to a higher dose can help alleviate some of the reactions to a new drug.

In OMF’s clinical trial, the Life Improvement Trial, participants go through dose titration for both drugs being investigated. Read more about the trial here.



Myalgic Encephalomyelitis / Chronic Fatigue Syndrome (ME / CFS) Post Treatment Lyme Disease Syndrome (PTLDS), Fibromyalgia Leading Research. Delivering Hope.Open Medicine Foundation®

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